There is an error in the log similar to this:
This error comes directly from the Intuit Software Development Kit (SDK) and indicates that it is seeing two possible QuickBooks files from which it can extract data, and that it is confused about which one it should communicate with.
There are five possible causes:
Cause 1. Make sure that there is only one copy of QuickBooks running at a time when performing a data refresh.
Cause 3. You can either change the QuickBooks company file name back to what was previously listed in the QQube Configuration Tool, or Add Company then Remove Company to reset the correct name. (You can't change the name of the company in the QQube Configuration Tool Directly).
Cause 4. Use the QQube Configuration Tool to change the path. This can only be done under the user where QQube was installed.
Cause 5. Open up QuickBooks to NO company file, before attempting to load multiple QuickBooks files. The Software Development Kit (SDK) does not allow developers to close a QuickBooks file that someone manually opened.
Cause 6. The synch takes place under the user where QQube is installed. However, regular users, in a multi-user implementation, may erroneously attempt to run the synchronizer under their own user name (or erroneously install an update under their own user name causing the synch to auto kick off), and cause errors like this to occur. A regular user is never a synch user unless you have a single-user on a workstation or laptop. If you are unfamiliar with the proper implementation, Please review the installation and requirements guides
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